A review on cosmos caudatus as a potential medicinal plant based on pharmacognosy, phytochemistry, and pharmacological activities

Ahda, Mustofa and Jaswir, Irwandi and Khatib, Alfi and Ahmed, Qamar Uddin and Syed Mohamad, Sharifah Nurul Akilah (2023) A review on cosmos caudatus as a potential medicinal plant based on pharmacognosy, phytochemistry, and pharmacological activities. International Journal of Food Properties, 26 (1). pp. 344-358. ISSN 1094-2912 E-ISSN 1532-2386

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Abstract

Cosmos caudatus (Asteraceae), is known as Ulam raja in Malaysia or kenikir in Indonesia also sometimes referred to as “King’s salad.” It is usually consumed as a salad and the leaves have been widely used as a traditional medicine due to their pharmacological activities and beneficial effects on human health. The leaves have been reported to contain several phytoconstituents such as flavonoids and their derivatives, other phenolics, and essential oil, while the roots only contain non-flavonoids. Furthermore, the leaves have been reported to contain a high total phenolic content (TPC) which is attributable for various activities including antidiabetes, antioxidant, anti-inflammation, antibacterial, antifungal, anti-osteoporosis, anti-hyperlipidemic, anticancer, antihypertensive, anti-hepatoprotective, and to manage fertility problems. However, further research needs to be done in order to determine whether C. caudatus is effective in treating thrombolytic and leishmanial disorder. Clinical study regarding the use of C. caudatus as an antidiabetic agent has been reported as a supplement to improve insulin resistance and sensitivity in type 2 diabetes patients [NCT02322268]. The findings of the toxicity tests revealed that the leaves are nontoxic and that they can be taken without risk. It is still need to conduct an additional in vitro and in vivo investigations to confirm various traditional claims about the therapeutic potential of this plant in the treatment of various ailments. This traditional medicinal plant’s genuine medicinal benefit will be further confirmed by additional clinical trials and toxicity assessments.

Item Type:	Article (Review)
Uncontrolled Keywords:	Cosmos caudatus; phytochemistry; Pharmacological activities; toxicity
Subjects:	Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	International Institute for Halal Research and Training (INHART) Kulliyyah of Pharmacy Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User:	Dr Qamar Uddin Ahmed
Date Deposited:	13 Mar 2023 08:37
Last Modified:	07 Jan 2024 13:43
URI:	http://irep.iium.edu.my/id/eprint/103959

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