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Maternal risk factors for group B streptococcus (GBS) vaginal colonization

Wahid, Hanan Hamimi and Bahez, Ayesha and Mustafa Mahmoud, Mohammed Imad Al-Deen and Hashim, Farih Najihah and Kamarudin, Norhidayah and Baharudin, Roesnita and Ahmad Mustafa, Ahmad Muzamir and Ismail, Hamizah (2022) Maternal risk factors for group B streptococcus (GBS) vaginal colonization. Acta Scientifica Malaysia (ASM), 6 (2). pp. 55-58. ISSN 2521-5051 E-ISSN 2521-506X

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Abstract

Approximately 18% of pregnant women are colonized with Group B streptococcus (GBS), which are βhemolytic, gram-positive bacteria. GBS conversion from the asymptomatic commensal in the vagina to an invasive pathogen predisposes the pregnant women to ascending intrauterine infection that tiggers preterm birth and initiate fetal and neonatal infections. The prevalence of colonizing GBS serotypes and sequence types (STs) are elucidated in this review in addition to the maternal components including demographical and obstetric factors that increase the risk for GBS colonization during pregnancy. Investigating the epidemiology is crucial for the development of new therapeutic and preventive measures to reduce the burden of invasive GBS disease worldwide including risk-factor based screening protocols.

Item Type: Article (Journal)
Uncontrolled Keywords: Group B Streptococcus, vaginal colonization, ascending intrauterine infection, preterm delivery
Subjects: Q Science > QR Microbiology
R Medicine > RG Gynecology and obstetrics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Basic Medical
Kulliyyah of Medicine > Department of Obstetric & Gynecology
Kulliyyah of Medicine > Department of Pathology & Lab Medicine
Depositing User: Dr Hanan Hamimi Binti Wahid
Date Deposited: 05 Oct 2022 12:34
Last Modified: 15 Nov 2022 12:09
URI: http://irep.iium.edu.my/id/eprint/100289

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