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Lymphocutaneous sporotrichosis: clinical suspicion when lesion is refractory to antibacterial treatment

Che' Man, Mohamad and Wan Mahmud, Wan Fatimah Suriyani and Ismail, Rasimah (2022) Lymphocutaneous sporotrichosis: clinical suspicion when lesion is refractory to antibacterial treatment. Brunei International Medical Journal, 18. pp. 99-102. ISSN 1560-5876 E-ISSN 2079-3146

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Sporotrichosis is a fungal infection caused by Sporothrix schenckii. It occurs worldwide especially in tropical and subtropical areas. It manifests as lymphocutaneous skin, fixed cutaneous or dis�seminated lesion following exposure to contaminated source like animals, plants, or abiotic com�ponents. We report a case of a 75-year-old lady with right foot ulcerative nodule which was re�fractory to repeated antibacterial treatment, and cultures were all negative including mycobacte�rium and fungus. Skin punch biopsy was also negative for granuloma or malignancy. Based on the history, physical examination and investigation findings, a clinical suspicion of lymphocutane�ous sporotrichosis was made. The patient was started on an empirical course of itraconazole 200mg od. The lesions responded well with 12 weeks of treatment. As clinicians we are occasion�ally faced with cases where investigations may not yield results that are helpful towards making a diagnosis and in such situations, we may need to start empirical treatment based on our best judgement.

Item Type: Article (Case Report)
Uncontrolled Keywords: Clinical diagnosis, Dermatomycoses, Skin ulcer, Sporotrichosis, Sporothrix schenckii
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011)
Date Deposited: 28 Aug 2022 15:43
Last Modified: 28 Aug 2022 15:43
URI: http://irep.iium.edu.my/id/eprint/99655

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