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Osteonecrosis of the jaw in patients taking atorvastatin: case series

Nordin, Jenizan and Ghazali, Ahmad Badruddin (2022) Osteonecrosis of the jaw in patients taking atorvastatin: case series. IUM Journal of Orofacial and Health Science, 3 (2). pp. 219-222. E-ISSN 2735-0584

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Osteonecrosis of the jawbones commonly seen in patients taking bisphosphonates, denosumab, and several antiangiogenic medications with several oral factors such as tooth extraction or dental infection. Currently, patients taking Simvastatin, a medication commonly used to treat hypercholesteremia, were reported of developing osteonecrosis of the jaw. Thus, it is important that clinicians know about the risk of osteonecrosis for patients taking this hypercholesteremia medication. It is not known if the undesirable effect only occurs with Simvastatin or other types of statin medication. We report in detail three cases of osteonecrosis of patients taking Atorvastatin calcium, a second-generation statin medication.

Item Type: Article (Case Report)
Uncontrolled Keywords: bisphosphonate, MRONJ, mevalonate pathway, osteonecrosis, statin
Subjects: R Medicine > RK Dentistry
R Medicine > RK Dentistry > RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
R Medicine > RK Dentistry > RK529 Oral Surgery-General Works
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Dentistry
Kulliyyah of Dentistry > Department of Oral Maxillofacial Surgery and Oral Diagnosis
Depositing User: Dr Ahmad Badruddin Ghazali
Date Deposited: 03 Aug 2022 14:02
Last Modified: 03 Aug 2022 14:05
URI: http://irep.iium.edu.my/id/eprint/99192

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