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Traditional uses, phytochemistry and biological activities of alocasia species: a systematic review

Arbain, Dayar and Sinaga, Lorenskia Maria Regina and Bakhtiar, M. Taher and Darnis, Deny Susanti and Zakaria, Zainul Amiruddin and Khotib, Junaidi (2022) Traditional uses, phytochemistry and biological activities of alocasia species: a systematic review. Frontiers: Frontiers in Pharmacology, 13. pp. 1-27. ISSN 1663-9812

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The genus Alocasia (Schott) G. Don consists of 113 species distributed across Asia, Southeast Asia, and Australia. Alocasia plants grow in tropical and subtropical forests with humid lowlands. Featuring their large green heart-shaped or arrow-shaped ear leaves and occasionally red- orange fruit, they are very popular ornamental plants and are widely used as traditional medicines to treat various diseases such as jaundice, snake bite, boils, and diabetes. This manuscript critically analysed the distribution, traditional uses, and phytochemical contents of 96 species of Alocasia. The numerous biological activities of Alocasia species were also presented, which include anti-cancer, antidiabetic and antihyperglycaemic, antioxidant, antidiarrhoea, antimicrobial and antifungal, antiparasitic (antiprotozoal and anthelminthic), antinociceptive and anti-inflammatory, brine shrimp lethality, hepatoprotective, anti- hemagglutinin, anti-constipation and diuretic, and radioprotective activities as well as acute toxicity studies. Research articles were acquired by the accessing three scientific databases comprising PubMed, Scopus, and Google Scholar. For this review, specific information was obtained using the general search term “Alocasia”, followed by the “plant species names” and “phytochemical” or “bioactivity” or “pharmacological activity”. The accepted authority of the plant species was referred from theplantlist.org. Scientific studies have revealed that the genus is mainly scattered throughout Asia. It has broad traditional benefits, which have been associated with various biological properties such as cytotoxic, antihyperglycaemic, antimicrobial, and anti-inflammatory. Alocasia species exhibit diverse biological activities that are very useful for medical treatment. The genus Alocasia was reported to be able to produce a strong and high-quality anti-cancer compound, namely alocasgenoside B, although information on this compound is currently limited. Therefore, it is strongly recommended to further explore the relevant use of natural compounds present in the genus Alocasia, particularly as an anti- cancer agent. With only a few Alocasia species that have been scientifically studied so far, more attention and effort is required to establish the link between traditional uses, active compounds, and pharmacological activities of various species of this genus.

Item Type: Article (Journal)
Uncontrolled Keywords: Alocasia, keladi liar, talas liar, bioactivities, giant taro
Subjects: Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science > Department of Chemistry
Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Kulliyyah of Science
Depositing User: Dr Deny Susanti Darnis
Date Deposited: 24 May 2022 15:40
Last Modified: 24 May 2022 15:40
URI: http://irep.iium.edu.my/id/eprint/98025

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