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Biotransformation of sesquiterpenoids: a recent insight

Aminudin, Nurul Iman and Ridzuan, Munirah and Darnis, Deny Susanti and Zainal Abidin, Zaima Azira (2021) Biotransformation of sesquiterpenoids: a recent insight. Journal of Asian Natural Products Research. pp. 1-44. ISSN 1028-6020 E-ISSN 1477-2213

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Sesquiterpenoids have been identified as natural compounds showing remarkable biological activities found in medicinal plants. There is great interest in developing methods to obtain sesquiterpenoids derivatives and biotransformation is one of the alternative methods for structural modification of complex sesquiterpenes structures. Biotransformation is a great drug design tool offering high selectivity and green method. The present review describes a comprehensive summary of biotransformation products of sesquiterpenoids and its structural modification utilizing a variety of biocatalysts including microorganisms, plant tissue culture and enzymes. This review covers recent literatures from 2007 until 2020 and highlights the experimental conditions for each biotransformation process.

Item Type: Article (Review)
Additional Information: 8125/89169
Uncontrolled Keywords: Biotransformation; sesqui-terpenoids; biocatalysts;drug-design
Subjects: Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science
Kulliyyah of Science > Department of Biotechnology
Kulliyyah of Science > Department of Chemistry
Depositing User: Dr Nurul Iman Aminudin
Date Deposited: 06 Apr 2021 16:00
Last Modified: 12 Aug 2021 08:58
URI: http://irep.iium.edu.my/id/eprint/89169

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