Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres )

Lim, Sheh Hong and Mohd Adib, Mohd Azrul Hisham and Abdullah, Mohd Shafie and Mohd Taib, Nur Hartini and Hassan, Radhiana and Abd. Aziz, Azian (2020) Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ). CFD Letters, 12 (10). pp. 1-14. ISSN 21801363

	PDF - Published Version Restricted to Repository staff only Download (1MB) | Request a copy
	PDF (SCOPUS) - Supplemental Material Restricted to Repository staff only Download (362kB) | Request a copy

Abstract

The recent diagnostic assessment of cerebrovascular disease makes use of computational fluid dynamics (CFD) to quantify blood flow and determine the hemodynamics factors contributing to the disease from patient-specific models. However, compliant, and anatomical patient-specific geometries are generally reconstructed from the medical images with different threshold values subjectively. Therefore, this paper tends to present the effect of extracted geometry with different threshold coefficient, Ctℎres by using a patient-specific cerebral aneurysm model. A set of medical images, digital subtraction angiography (DSA) images from the real patient diagnosed with internal carotid artery (ICA) aneurysm was obtained. The threshold value used to extract the patient-specific cerebral aneurysm geometry was calculated by using a simple threshold determination method. Several threshold coefficients, Ctℎres such as 0.2, 0.3, 0.4, 0.5 and 0.6 were employed in the image segmentation creating three-dimensional (3D) realistic arterial geometries that were then used for CFD simulation. As a result, we obtained that the volume of each patient-specific cerebral aneurysm geometry decreases as the threshold coefficient, Ctℎres increases. There is dislocation of artery attached to the ICA aneurysm geometry occurred at a high threshold coefficient, Ctℎres . Besides, the physical changes also bring remarkable physiological effect on the wall shear stress (WSS) distribution and velocity flow field at the patient-specific cerebral aneurysm geometry reconstructed with different threshold coefficient, Ctℎres

Item Type:	Article (Journal)
Uncontrolled Keywords:	Cerebral aneurysm;threshold coefficient; hemodynamics; wall shear stress; computational fluid dynamics
Subjects:	R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Radiology
Depositing User:	Suhani Saarani
Date Deposited:	09 Feb 2021 17:47
Last Modified:	09 Feb 2021 17:47
URI:	http://irep.iium.edu.my/id/eprint/88301

Actions (login required)

View Item