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Mode of delivery, order of birth, parental age gap and autism spectrum disorder among Malaysian children: a case-control study

Galvan, Jo Ann Andoy and Ramalingam, Prabhagari Nair and Patil, Sapna Shridhar and Shobri, Muhammad Aminul Syahmi and Chinna, Karuthan and Sahrir, Muhammad Sabri and Chidambaram, Kumarappan (2020) Mode of delivery, order of birth, parental age gap and autism spectrum disorder among Malaysian children: a case-control study. Heliyon, 6 (10). pp. 1-5. E-ISSN e05068

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Abstract

Rising prevalence of autism spectrum disorders (ASD) in the last decades has led research to focus on the diagnosis and identification of factors associated with ASD. This paper sought for possible factors that put children at risk for ASD. In this study, we investigated the association between ASD and parental ages, parental age gaps, birth order and birth delivery method in Malaysian population. In this school-based case control study, 465 children with ASD 464 controls participated. Questionnaires were distributed to the parents of the selected children through the respective principals. Among the tested variables, Caesarean section (OR = 1.63, 95% CI 1.20, 2.20), earlier order of birth in the family (OR = 0.68, 95% CI 0.59, 0.77) and increasing gap in parental ages (OR = 1.04, 95% CI 1.001, 1.07) were significantly associated with ASD. This study concludes that Caesarean section, earlier order of birth in the family and increasing gap in parental age are independent risk factors for developing autism among Malaysian children. **************************************

Item Type: Article (Journal)
Additional Information: 3267/83513
Uncontrolled Keywords: Epidemiology, Public health, Behavioral medicine, Pediatrics, Educational psychology, Psychology, Cognitive psychology, Autism spectrum disorder, Malaysia, Parental age, Birth delivery, Birth order, Parental age gap
Subjects: L Education > L Education (General)
R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Education
Kulliyyah of Education > Department of Language & Literacy
Depositing User: Dr Muhammad Sabri Sahrir
Date Deposited: 21 Oct 2020 18:04
Last Modified: 21 Oct 2020 18:04
URI: http://irep.iium.edu.my/id/eprint/83513

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