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Anti-diabetic medication burden amongst older persons with diabetes and associated quality of life

Shalihin, Mohd Shaiful Ehsan and Fauzi, Abdullah and Zulkifli, Nurul Afiqah and Abdul Aziz, Azrul Aziz (2020) Anti-diabetic medication burden amongst older persons with diabetes and associated quality of life. Medical Journal of Malaysia, 75 (5). pp. 525-530. ISSN 0300-5283

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Background: Older persons with diabetes are the major demographic of diabetic patients followed up in primary health clinics. Despite their increasing age and morbidities, They are still being managed strictly towards good sugar control in order to achieve the ideal HbA1c level without taking their quality of life into consideration. This study aimed to determine the prevalence in the use of antidiabetic drugs among older persons with diabetes and its association with their quality of life. Methodology: A cross-sectional study was conducted among 269 older persons with diabetes in all government health clinics in Kuantan using Diabetes Quality of Life questionnaire. SPSS version 23 was used for the statistical analysis. Results: Majority of the respondents were females (61%), Malays (84.8%), pensioners (54.3%) with education up to primary school (52%) and are staying with family members (93.7%). Most of the patients were on two antidiabetic agents (48%) followed by a single antidiabetic agent (32%). Despite the risk of hypoglycaemia, 0.4% of them are on glibenclamide. The use of insulin is still common among 21% of them that are on intermediate-acting insulin, 15.6% on premixed insulin and 7.8% on short-acting insulin. Those taking a higher number of antidiabetic agents were found to be associated with poorer quality of life (p=0.001) compared to those taking one or two antidiabetic medications. Those on insulin also have significantly poorer quality of life score (p=0.012). Conclusion: Despite aiming for controlled diabetes, older persons suffer poor quality of life with further intensification of their antidiabetic medications according to the guidelines. This includes the complexity of insulin usage and polypharmacy, which contribute to the low quality of life score.

Item Type: Article (Journal)
Additional Information: 6934/83324
Uncontrolled Keywords: Older persons, Diabetic, Antidiabetic agents, Quality of Life
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
R Medicine > RT Nursing
R Medicine > RZ Other systems of medicine > RZ400 Mental healing
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011)
Depositing User: Dr Mohd Shaiful Ehsan Shalihin
Date Deposited: 28 Sep 2020 15:16
Last Modified: 23 Nov 2020 16:43
URI: http://irep.iium.edu.my/id/eprint/83324

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