Genetics of malocclusion: a review

Mokhtar@Makhtar, Khairani Idah and Abu Bakar, Noraini and Md Ali @ Tahir, Aisyah Hanani (2020) Genetics of malocclusion: a review. International Journal of Orofacial and Health Sciences, 1 (1). pp. 4-10. ISSN 2716-5434

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Abstract

Malocclusion is one of the most common craniofacial problems observed worldwide. Affected individuals suffer not only from aesthetic concerns but also from functional problems, such as with mastication and pronunciation. The prevalence of malocclusion in East Asians is higher than in other races. Reports have shown besides environmental factors, there is association between certain types of malocclusion with specific genes. Positive association of mandibular prognathism has been implicated to genes such as Matrilin-1; while mutation in DUSP6 has also been shown to contribute to the incidence of malocclusion. This review aimed to briefly discuss the involvement of other additional genes such as MYO1H and PAX9 in the incidence of malocclusion as observed from our local institution.

Item Type:	Article (Review)
Additional Information:	7172/80999
Uncontrolled Keywords:	malocclusion, genes
Subjects:	R Medicine > RK Dentistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Fundamental Dental and Medical Sciences Kulliyyah of Dentistry > Department of Paediatric Dentistry and Dental Public Health
Depositing User:	Assoc Prof Khairani Idah Mokhtar
Date Deposited:	23 Jun 2020 17:08
Last Modified:	23 Jun 2020 17:08
URI:	http://irep.iium.edu.my/id/eprint/80999

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