Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum

Zamimi, Nurul Najwa and Ab. Halim, Noorhazayti and Darnis, Deny Susanti and Lestari, Widya and Md Mustafa, Md Muziman Syah (2019) Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum. International Journal of Research in Pharmaceutical Sciences, 10 (4). pp. 2705-2710. ISSN 0975-7538

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Abstract

Sargassum polycystum is a brown seaweed, which has been reported to contain various phytoconstituents especially antimicrobial properties. However, the study on phytochemical components and biological activities of S. polycystum are yet fully understood. Therefore, the objectives of this study are to evaluate the best extraction solvents for S. polycystum and to determine the percentage of phytocomponents obtained in the n-hexane, dichloromethane (DCM) and methanol extracts of S. polycystum via Gas Chromatography-Mass Spectrometry (GC-MS) analysis. S. polycystum was collected from the coastal area of Sabah, Malaysia. After collection, it was rinsed, dried and extracted with n-hexane, DCM and methanol by soxhlet extraction. The fatty acid compounds (FAME) analysis was done using The Perkin Elmer Turbo Mass Spectrometer. This study showed that methanol is the most efficient solvent as it produced the highest extraction yield with 3.83%, followed by n-hexane with 1.69% and lastly DCM with 0.59% in S. polycystum. On top of that, this study has found 19 phytocomponents in all extraction methods of S. polycystum, which have been proven to possess antibacterial constituents such as palmitic acid, myristic acid, oleic acid, pentadecanoic acid and behenic acid as assessed by GC-MS analysis.

Item Type:	Article (Journal)
Additional Information:	5869/75520
Uncontrolled Keywords:	Fatty acid, Gas chromatography-mass spectrometry, Phytocomponents, Sargassum polycystum, Seaweeds
Subjects:	R Medicine > RM Therapeutics. Pharmacology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Allied Health Sciences > Department of Optometry and Visual Science Kulliyyah of Dentistry > Department of Paediatric Dentistry and Dental Public Health Kulliyyah of Science > Department of Chemistry Kulliyyah of Allied Health Sciences Kulliyyah of Dentistry Kulliyyah of Science
Depositing User:	Asst Prof Noorhazayti Ab. Halim
Date Deposited:	22 Oct 2019 09:52
Last Modified:	20 Apr 2022 14:25
URI:	http://irep.iium.edu.my/id/eprint/75520

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