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Characterization And Classification Of Bioactive Compound In Natural Products By FTIR And Multivariate Data Analysis

Mohamed Azmin, Nor Fadhillah and Amid, Azura and Asnawi, Ani Liza (2018) Characterization And Classification Of Bioactive Compound In Natural Products By FTIR And Multivariate Data Analysis. Project Report. UNSPECIFIED.

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Abstract

Bioactive compounds are one of the natural products used especially for medicinal, pharmaceutical and food application. Increasing research performed on the extraction, isolation and identification of bioactive compounds, however non to date has explored on the identification of flavonoids classes. Therefore, this study was focused on the development of algorithm for rapid identification of flavonoids classes which are flavanone, flavone and flavonol. Fourier Transform Infrared (FTIR) spectroscopy coupled with multivariate statistical data analysis, which is Principal Component Analysis (PCA) was performed. The results showed that the flavonoids classes were identified according to spectral region assigned using the PCA algorithm based on the FTIR spectrum of the samples. The study concluded that FTIR coupled with PCA analysis can be used as a molecular fingerprint for rapid identification of flavonoids classes. The comparative studies of other flavonoids classes are still under investigation using the same method.

Item Type: Monograph (Project Report)
Uncontrolled Keywords: Flavonoid, Principal Component Analysis, Multivariate Data Analysis, FTIR,
Subjects: Q Science > QA Mathematics > QA300 Analysis
Q Science > QD Chemistry
T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Dr Nor Fadhillah Mohamed Azmin
Date Deposited: 30 Mar 2021 10:53
Last Modified: 30 Mar 2021 10:53
URI: http://irep.iium.edu.my/id/eprint/71669

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