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Integrated data analysis model for screening cell line producer

Mohamed Azmin, Nor Fadhillah (2018) Integrated data analysis model for screening cell line producer. In: Multifaceted protocol in biotechnology. Springer Nature, Singapore, pp. 227-234. ISBN 978-981-13-2256-3

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Abstract

The complexity of bioprocess data generated from the manufacture of recombinant monoclonal antibodies cell line sparks the chemometrics study of the datasets. The ultimate goal is to form a link between the data and its underlying biological patterns. A concatenated protocol, specifically discrete wavelet transform and multiway principal component analysis techniques, is recommended to successfully extract meaningful information from the complex datasets.

Item Type: Book Chapter
Additional Information: 4051/70578
Uncontrolled Keywords: Cell lines · Monoclonal antibodies · Screening · Selection · Algorithm · Fourier transform infrared (FTIR) · Near infrared (NIR) · Electrospray ionization (ESI-MS) · Principal component analysis (PCA) · Binning · Wavelet transform · Score plot · Loading plot · Contribution plot
Subjects: T Technology > TP Chemical technology > TP200 Manufacture and use of chemicals
T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Dr Nor Fadhillah Mohamed Azmin
Date Deposited: 11 Feb 2019 11:37
Last Modified: 11 Feb 2019 12:49
URI: http://irep.iium.edu.my/id/eprint/70578

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