Electrospun Poly (Vinyl Alcohol) (PVA) fiber mats as carriers for extract from agarwood branch

Mohd Noor, Najihah and Hashim, Yumi Zuhanis Has-Yun and Ahmad Nor, Yusilawati and Tshai, Albert and Wan Salim, Wan Wardatul Amani and Sopyan, Iis (2018) Electrospun Poly (Vinyl Alcohol) (PVA) fiber mats as carriers for extract from agarwood branch. In: International Conference on Halal Innovation in Products and Services 2018 (i-CHIPS 2018), 13th-14th July 2018, Haat Yai, Songkhla, Thailand.

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Abstract

In this paper, electrospinning was carried out to determine the optimum level for selected process parameters that produce poly (vinyl alcohol) (PVA) loaded agarwood branch ethanolic extract (ABEE) fiber mat which is potentially useful for wound healing application. The process parameters to optimize the fabrication of ABEE-loaded PVA fiber mats were studied using One-Factor-at-a-Time (OFAT). The parameters include voltage supply (kV), flow rate (ml/h) and collection distance (cm). The optimal molecular weight of PVA for the preparation of smooth and beadless PVA nanofiber in this study was 145,000 g/mol. The diameter of the electrospun of both PVA neat and ABEE-loaded PVA fiber mats were 312.2 nm and 431.2 nm; respectively with the formation of smooth fibers with minimum beadings. Based on the OFAT method, the optimal process parameters for fabrication of PVA/ABEE fiber mats were spinned at the voltage of 20 kV, flow rate of 0.7 ml/h and collection distance of 14 cm. The agarwood extract incorporated-fiber mats could be further developed into alternative halal transdermal patches for wound healing.

Item Type:	Conference or Workshop Item (Plenary Papers)
Additional Information:	3774/66279
Uncontrolled Keywords:	Agarwood, Electrospinning, Halal, Polyvinyl alcohol
Subjects:	Q Science > Q Science (General) T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering Kulliyyah of Engineering > Department of Biotechnology Engineering Kulliyyah of Engineering > Department of Manufacturing and Materials Engineering
Depositing User:	DR YUMI ZUHANIS HAS-YUN HASHIM
Date Deposited:	22 Oct 2018 09:53
Last Modified:	22 Oct 2018 09:54
URI:	http://irep.iium.edu.my/id/eprint/66279

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