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Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design

Subara, Deni and Jaswir, Irwandi and Alkhatib, Ma'an Fahmi Rashid and Noorbatcha, Ibrahim Ali (2017) Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design. In: International Conference on Advances in Manufacturing and Materials Engineering 2017 (ICAMME17), 8-9 August 2017, Kuala Lumpur, Malaysia.

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Abstract

The aim of this experiment is to screen and to understand the process variables on the fabrication of fish gelatin nanoparticles by using quality-design approach. The most influencing process variables were screened by using Plackett-Burman design. Mean particles size, size distribution, and zeta potential were found in the range 240±9.76 nm, 0.3, and −9 mV, respectively. Statistical results explained that concentration of acetone, pH of solution during precipitation step and volume of cross linker had a most significant effect on particles size of fish gelatin nanoparticles. It was found that, time and chemical consuming is lower than previous research. This study revealed the potential of quality-by design in understanding the effects of process variables on the fish gelatin nanoparticles production.

Item Type: Conference or Workshop Item (Plenary Papers)
Additional Information: 5784/61900
Uncontrolled Keywords: Significance variables; Fabrication of fish gelatin; Nanoparticles by Plackett-Burman design
Subjects: T Technology > TP Chemical technology
T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Prof. Dr. Ibrahim Ali Noorbatcha
Date Deposited: 13 Feb 2018 08:44
Last Modified: 11 Jul 2018 06:35
URI: http://irep.iium.edu.my/id/eprint/61900

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