Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa

Althunibat, Osama Yousef and Qaralleh, Haitham and Abboud, Muayad and Khleifat, Khaled and Majali, Ibrahim S. and Darnis, Deny Susanti and Aldal'In, Hammad Khalifeh H. and Yassin Ahmed Al-dalin, Sati (2016) Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa. Journal of Pure and gyApplied Microbiology, 10 (1). pp. 367-374. ISSN 0973-7510 (In Press)

	PDF (In press) - Submitted Version Restricted to Repository staff only Download (161kB) | Request a copy
	PDF (Scopus) - Supplemental Material Restricted to Repository staff only Download (539kB) | Request a copy

Abstract

his study was designed to evaluate the antibacterial activity of Thymus capitatus and two of its major components namely thymol and carvacrol. The dried leaves were extracted using soxhlet apparatus. Thymol and carvacrol were isolated using normal phase column chromatography. The antibacterial activity of the leaves extract, thymol and carvacrol were estimated using agar disc diffusion and broth dilution methods against four bacterial strains. The leaves extract was found to show a broad spectrum of antibacterial activity against all the tested bacterial strains. Pseudomonas aeruginosa was the most sensitive bacteria. The purified compounds exhibited relatively stronger antibacterial activity than the extract. Thymol fraction exhibited stronger antibacterial activity than carvacrol. Thymol fraction exhibited MIC values ranging from 0.005 – 0.008 mg/mL while carvacrol fraction exhibited MIC values ranging from 0.007 – 0.008 mg/mL.

Item Type:	Article (Journal)
Additional Information:	5641/61528
Uncontrolled Keywords:	Thymus capitatus, thymol, carvacrol, Pseudomonas aeruginosa
Subjects:	Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science
Depositing User:	Dr Deny Susanti Darnis
Date Deposited:	30 Jan 2018 08:31
Last Modified:	11 Jul 2018 08:28
URI:	http://irep.iium.edu.my/id/eprint/61528

Actions (login required)

View Item