Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism

Ansari, Nor Faezah and Annuar, M. Suffian (2017) Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism. Journal of Macromolecular Science: Pure and Applied Chemistry, 55 (1). pp. 66-74. ISSN 1060-1325 E-ISSN 1520-5738

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Abstract

Glycerol 1,3-diglycerolate diacrylate (GDD) was graft copolymerized onto poly(3-hydroxyoctanoate-co-3- hydroxyhexanoate) P(3HO-co-3HHX) to render the latter more hydrophilic. Grafting of P(3HO-co-3HHX) backbone was performed using benzoyl peroxide as free radical initiator in homogenous acetone solution. The graft copolymer of P(3HO-co-3HHX)-g-GDD was characterized using spectroscopic and thermal methods. The presence of GDD monomer in the grafted P(3HO-co-3HHX) materials linked through covalent bond was indicated by spectroscopic analyses. Different parameters affecting the graft yield viz. monomer concentration, initiator concentration, temperature and reaction time were also investigated. Water uptake measurement showed that P(3HO-co-3HHX)-g-GDD copolymer became more hydrophilic as the GDD concentration in the copolymer increased. Introduction of hydroxyl groups via grafted GDD monomers improved the wettability and imparted amphiphilicity to the graft copolymer, thus potentially improving their facility for cellular interaction. Thermal stability of grafted copolymer reduced with increased grafting yield. The activation energy, Ea, for the graft copolymerization was calculated at » 51 kJ mol¡1. Mechanism of grafting reaction was also proposed.

Item Type:	Article (Journal)
Additional Information:	8327/60340
Uncontrolled Keywords:	Functionalization; Mediumchain-length poly-3- hydroxyalkanoates; Glycerol 1,3-diglycerolate diacrylate; Graft copolymerization; Mechanism
Subjects:	Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science Kulliyyah of Science > Department of Biotechnology
Depositing User:	DR NOR FAEZAH ANSARI
Date Deposited:	18 Dec 2017 10:07
Last Modified:	25 Jun 2019 10:45
URI:	http://irep.iium.edu.my/id/eprint/60340

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