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Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia

Shahadan, Siti Zuhaidah and Daud, Azlina and Md. Isa, Muhammad Lokman and Mohd Rasani, Ali Aminuddin and Ibrahim, Muhammad and Draman, Samsul (2018) Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia. International Medical Journal Malaysia, 17 (1). pp. 79-86.

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Abstract

Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a measure of abdominal obesity and high-sensitivity C-reactive protein as an indicator of inflammation status among Malay obese adults in Kuantan, Pahang. Materials and Methods: Ninety-three apparently healthy obese adults (BMI between 27.5 and 39.9 kg/m2) aged between 20 to 62 years old were recruited in this study (68% men and 32% women). Circumference tape was used to measure the waist circumference and fasting venous blood was obtained to determine the high-sensitivity C-reactive protein level. Results: On average, the waist circumference of obese men and women was 103 cm (SD = 8.7) and 94 cm (SD = 7.0), respectively. The median (IQR) of the hs-CRP level of the study participant was 3.80 mg/L (1.5, 10.1). The Kendall’s Tau correlation reveals that there is a significant positive linear correlation between waist circumference and hs-CRP level in obese men (r (30) = 0.355, p = 0.006) and women (r (63) = 0.177, p = 0.043). Conclusion: There is a significant inter-relationship between waist circumference and hs-CRP level among apparently healthy obese adults in Kuantan, Pahang. This study suggests that assessment of hs-CRP level is beneficial to predict the risk for future cardiovascular disease event and facilitate the management of obesity in this population. A prospective clinical study is recommended to confirm the findings.

Item Type: Article (Journal)
Additional Information: 5226/58135
Uncontrolled Keywords: obesity, inflammation, adults
Subjects: R Medicine > RT Nursing
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Nursing
Depositing User: Assist. Prof. Dr. Azlina Daud
Date Deposited: 05 Sep 2017 12:02
Last Modified: 24 Jan 2019 09:42
URI: http://irep.iium.edu.my/id/eprint/58135

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