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Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus

Tunna, Tasnuva Sarwar and Sarker, Md. Zaidul Islam and Ahmed, Qamar Uddin and Md. Jaffri, Juliana and Ferdoush, Sahena (2016) Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016), 15th-16th Aug. 2016, Kuantan, Pahang. (Unpublished)

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Abstract

Medicinal plants and various extracts are traditionally used to treat ailments, disease and infections. Traditionally, organic solvents, water and oil were and are still used for the extraction of herbal medicine and often boiling (percolation) and vigorous techniques to separate the bioactive compounds were employed. Along with the advent of green technology and extraction methods, organic solvent-free extract preparation is on the rise. The current study aimed to undergo enrichment of chosen pre-isolated anti-diabetic compounds from M. pudica. The current study was employed using supercritical CO2 extraction (SFE) and subcritical CO2 Soxhlet by studying parameters of temperature, pressure, modifier or co-solvent and flow rate of CO2. It was found that the SFE and CO2-Soxhlet can be utilized to collect extract enriched with anti-diabetic compounds, which are stigmasterol, quercetin and avicularin from M. pudica in a clean and healthier method for future anti-diabetic implications.

Item Type: Conference or Workshop Item (Plenary Papers)
Additional Information: 6605/55757
Uncontrolled Keywords: Enriched extracts,anti-diabetic compounds, weed, M. Pudica,supercritical, subcritical carbon dioxide extractions, diabetes mellitus
Subjects: Q Science > Q Science (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy
Kulliyyah of Science
Depositing User: Professor Dr. Md. Zaidul Islam Sarker
Date Deposited: 07 Mar 2017 11:23
Last Modified: 07 Mar 2017 11:23
URI: http://irep.iium.edu.my/id/eprint/55757

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