Porous hydroxyapatite for artificial bone applications

Iis, Sopyan and Mel, Maizirwan and Singh, Ramesh and Khalid, Kamarul Ariffin (2007) Porous hydroxyapatite for artificial bone applications. Science and Technology of Advanced Materials, 8 (1-2). pp. 116-123. ISSN 1468-6996

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Abstract

Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and drug delivery. In bone tissue engineering it has been applied as filling material for bone defects and augmentation, artificial bone graft material, and prosthesis revision surgery. Its high surface area leads to excellent osteoconductivity and resorbability providing fast bone ingrowth. Porous HA can be produced by a number of methods including conversion of natural bones, ceramic foaming technique, polymeric sponge method, gel casting of foams, starch consolidation, microwave processing, slip casting, and electrophoretic deposition technique. Some of these methods have been combined to fabricate porous HA with improved properties. These combination methods have yielded some promising results. This paper discusses briefly fundamental aspects of porous HA for artificial bone applications as well as various techniques used to prepare porous HA. Some of our recent results on development ofmporous HA will be presented as well.

Item Type:	Article (Journal)
Additional Information:	4809/5477
Uncontrolled Keywords:	porous hydroxyapatite, artificial bone
Subjects:	T Technology > TP Chemical technology > TP155 Chemical engineering T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering
Depositing User:	Dr Maizirwan Mel
Date Deposited:	31 Mar 2012 06:26
Last Modified:	14 Sep 2015 12:21
URI:	http://irep.iium.edu.my/id/eprint/5477

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