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Exercise improved age-associated changes in the carotid blood velocity waveforms

Noor Azmi, Azran Azhim and M. , Katai and M., Akutagawa and Y., Hirao and K., Yoshizaki and S., Obara and M. , Nomura and H., Tanaka and H., Yamaguchi and Y., Kinouchi (2007) Exercise improved age-associated changes in the carotid blood velocity waveforms. Journal of Biomedical & Pharmaceutical Engineering , 1 (1). pp. 17-26. ISSN 1793-4532

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Physiological blood flow velocity in common carotid artery (CCA) is altered markedly with advancing age. It is unknown that regular aerobic exercise is able to improve blood flow velocity waveforms in either healthy young or healthy older individuals. We investigate the role of regular exercise on the age-associated alterations in blood velocity waveforms in CCA by using cross-sectional and intervention approaches. First, we study 91 putatively healthy volunteers with age range of 20-76 years: 65 subjects are sedentary and 26 subjects are regular exercisetrained. We assess the blood velocities at rest in peak systolic (S1), second systolic (S2), incisura between systole (I) and peak diastolic (D), and end-diastolic (d) in young, middle-aged and older subjects. Blood velocities in S1 are higher in exercise-trained, whereas S2, D and d are not different between trained and sedentary individuals. However, the indices of S1/S2 and D/I have marked higher values in exercise-trained adults. Second, we study 7 young sedentary healthy subjects before and after 1-month aerobic exercise intervention. The aerobic exercise increases whole velocity waveforms in CCA with association of decreased heart rate. In conclusion, regular exercise improves age-associated decrease in blood flow velocities in the healthy young, middle-aged and older individuals and restores levels after 1-month exercise in previously sedentary young men.

Item Type: Article (Journal)
Additional Information: 7380/44122
Uncontrolled Keywords: Doppler ultrasound, portable telemetry system, blood velocity waveform, age, aerobic exercise training
Subjects: T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science > Department of Biotechnology
Depositing User: Ir Dr Azran Azhim Noor Azmi
Date Deposited: 17 Aug 2015 11:28
Last Modified: 17 Aug 2015 11:28
URI: http://irep.iium.edu.my/id/eprint/44122

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