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Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum

Noorbatcha, Ibrahim Ali and Ahmad, Abdul Aziz and Mohd. Salleh, Hamzah (2014) Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum. In: International Research, Invention and Innovation Exhibition 2014 (IRIIE2014), 11th -13th June 2014, Cultural Activity Center (CAC), Internatioanal Islamic University Malaysia. (Unpublished)

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Abstract

Cellulose is the most abundant biopolymer on earth. Enzymatic degradation of this biopolymer is a crucial step toward its conversion to bioethanol. However the current cellulosic enzymes are unable to withstand high temperature of industrial processes. In this work we use computer simulations to predict thermostable endoglucanase. The molecular dynamics simulation is a powerful tool that can be used to study the enzymes behaviour at high temperature. On the basis of computer simulations we have predicted a mutant endoglucanase with improved thermal stability properties.

Item Type: Conference or Workshop Item (Poster)
Additional Information: 3704/41304
Uncontrolled Keywords: cellulose, thermostable endoglucanase
Subjects: T Technology > TP Chemical technology
T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Prof. Dr. Ibrahim Ali Noorbatcha
Date Deposited: 13 Feb 2015 10:03
Last Modified: 19 Jun 2018 16:01
URI: http://irep.iium.edu.my/id/eprint/41304

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