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Homology modeling of Pyranose 2-Oxidase from Phanerochaete Chrysosporium

Ibrahim Ali , Noorbatcha and Harithuddin, Ahmad Sidqi and Ramli, Siti Khairani and Othman, Raihan and Mohd. Salleh, Hamzah (2013) Homology modeling of Pyranose 2-Oxidase from Phanerochaete Chrysosporium. In: International Conference on Biotechnology Engineering (ICBioE 2013), 2 – 4 Jul 2013, Kuala Lumpur, Malaysia.

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Abstract

Currently, most of the demands for energy relied on petroleum products. Nevertheless, the issues of energy security, economics and environment has led to the breakthrough of biofuel cells (BFCs) technology as one of the promising solution to the problems. However, the performance of BFCs need to be improved in order to compete with the existing technologies. One way to improve the efficiency of BFCs is to ensure that the enzyme used as the catalyst in BFCs, in this case, pyranose 2-oxidase (P2Ox) has better binding characteristic and broad substrate specificity. For this purpose, studies on three-dimensional (3-D) structure of P2Ox enzyme can offer insights on the structurefunction correlations. Unfortunately, at present there is no available crystal structure of P2Ox from P. chrysosporium (PcP2Ox). Thus, in this study homology modelling was used as the reliable alternative method to predict the 3-D structure of PcP2Ox enzyme. The structural information obtained here can provide necessary information to model and design more efficient PcP2Ox.

Item Type: Conference or Workshop Item (Full Paper)
Additional Information: 3704/34145
Uncontrolled Keywords: homology modelling, pyranose-2-oxidase, Phanerochaete chrysosporium
Subjects: T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Prof. Dr. Ibrahim Ali Noorbatcha
Date Deposited: 15 Jan 2014 09:19
Last Modified: 15 Jan 2014 09:19
URI: http://irep.iium.edu.my/id/eprint/34145

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