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Optimization of supercritical CO2 extraction of fish oil from viscera of African Catfish (Clarias gariepinus)

Sarker, Md. Zaidul Islam and Selamat, Jinap and Md. Ahsan Habib, Abu Sayem and Ferdosh, Sahena and Akanda, Mohamed Jahurul Haque and Md. Jaffri, Juliana (2012) Optimization of supercritical CO2 extraction of fish oil from viscera of African Catfish (Clarias gariepinus). International Journal of Molecular Sciences, 13 (9). pp. 11312-11322. ISSN 1422-0067

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Fish oil was extracted from the viscera of African Catfish using supercritical carbon dioxide (SC-CO2). A Central Composite Design of Response Surface methodology (RSM) was employed to optimize the SC-CO2 extraction parameters. The oil yield (Y) as response variable was executed against the four independent variables, namely pressure, temperature, flow rate and soaking time. The oil yield varied with the linear, quadratic and interaction of pressure, temperature, flow rate and soaking time. Optimum points were observed within the variables of temperature from 35 °C to 80 °C, pressure from 10 MPa to 40 MPa, flow rate from 1 mL/min to 3 mL/min and soaking time from 1 h to 4 h. However, the extraction parameters were found to be optimized at temperature 57.5 °C, pressure 40 MPa, flow rate 2.0 mL/min and soaking time 2.5 h. At this optimized condition, the highest oil yields were found to be 67.0% (g oil/100 g sample on dry basis) in the viscera of catfish which was reasonable to the yields of 78.0% extracted using the Soxhlet method.

Item Type: Article (Journal)
Additional Information: 6605/25714
Uncontrolled Keywords: supercritical fluid extraction, catfish fish oil, viscera, response surface methodology
Subjects: Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Kulliyyah of Science
Depositing User: Professor Md. Zaidul Islam Sarker
Date Deposited: 13 Sep 2012 08:53
Last Modified: 31 Dec 2015 11:54
URI: http://irep.iium.edu.my/id/eprint/25714

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