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Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study

Kawasaki, Ryo and Che Azemin, Mohd. Zulfaezal and Kumar, Dinesh Kant and Tan, Ava Grace and Liew, Gerald and Wong, Tien Yin and Mitchell, Paul and Wang, Jie Jin (2011) Fractal dimension of the retinal vasculature and risk of stroke : a nested case-control study. NEUROLOGY, 76. pp. 1766-1770. ISSN 0028-3878

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Abstract

Recent studies show associations between retinal vascular changes and small infarcts detected on brain imaging, or clinical stroke. Fractal dimension has been used as a global measure of the geometric pattern of the retinal vasculature potentially representing the complex branching pattern of the microvasculature, including the cerebral microvasculature. We have developed an automatic method to assess spectrum fractal dimension (SFD) of the retinal microvasculature using Fourier-transformed images. Two previous studies have reported cross-sectional associations between retinal fractal dimension and lacunar stroke. In this study, we aimed to examine the association between baseline SFD and stroke incidence using a case-control sample nested in the Blue Mountains Eye Study (BMES).

Item Type: Article (Journal)
Additional Information: 6768/24914
Uncontrolled Keywords: retinal vascular, stroke
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RE Ophthalmology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Allied Health Sciences > Department of Optometry and Visual Science
Depositing User: Dr. Mohd Zulfaezal Che Azemin
Date Deposited: 30 Apr 2013 15:09
Last Modified: 30 Apr 2013 16:28
URI: http://irep.iium.edu.my/id/eprint/24914

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