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Escherichia coli glucuronylsynthase: an engineered enzyme for the synthesis of β-glucuronides

Wilkinson, Shane M. and Liew, Chu W. and Mackay, Joel P. and Mohd. Salleh, Hamzah and Withers, Stephen G. and McLeod, Malcolm D. (2008) Escherichia coli glucuronylsynthase: an engineered enzyme for the synthesis of β-glucuronides. Organic Letters, 10 (8). pp. 1585-1588. ISSN 1523-7060

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Abstract

The glycosynthase derived from E. coli β-glucuronidase catalyzes the glucuronylation of a range of primary, secondary, and aryl alcohols with moderate to excellent yields. The procedure provides an efficient, stereoselective, and scalable single-step synthesis of β-glucuronides under mild conditions.

Item Type: Article (Journal)
Additional Information: 1813/23428
Uncontrolled Keywords: glucuronide; glucuronosyltransferase
Subjects: T Technology > T Technology (General) > T175 Industrial research. Research and development
T Technology > TA Engineering (General). Civil engineering (General) > TA164 Bioengineering
T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Dr Hamzah Mohd. Salleh
Date Deposited: 22 Jul 2013 12:46
Last Modified: 22 Jul 2013 12:46
URI: http://irep.iium.edu.my/id/eprint/23428

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