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Improvement of extraction processing conditions for antifungal compounds from Alpinia galanga

Ahmad Raus, Raha and Addnan, Nor Hafizah and Mat Amin, Noriha and Aini Shohaimi, Syamsiah (2011) Improvement of extraction processing conditions for antifungal compounds from Alpinia galanga. In: Current Research and Development in Biotechnology Engineering at IIUM (volume II). IIUM Press, Kuala Lumpur, pp. 379-385. ISBN 978-967-418-151-2

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Alpinia galanga IS a rhizomatous herbaceous perennial plant of the ginger family, Zingiberaceae that is known for its antifungal property. In this study optimization of extraction processing conditions were determined to obtain maximum yield of antifungal compounds from A. galanga. Optimization experiments designed by Box-Behnken (Design Expert Software) were carried out with three parameters considered namely agitation, extraction time and temperature. Analysis of results was done statistically using Analysis of Variance (ANOVA). The regression equation analysis showed that the optimum condition in producing antibacterial compound was temperature 2rC, time 11.3 hours and agitation level 323 rpm which gave the maximum diameter of zone inhibition (39.1 mm).

Item Type: Book Chapter
Additional Information: 3911/20826
Uncontrolled Keywords: Extraction, antifungal activity. Alpinia galanga, Box-Behnken
Subjects: T Technology > TP Chemical technology
T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Dr Raha Ahmad Raus
Date Deposited: 26 Nov 2012 15:17
Last Modified: 26 Nov 2012 15:18
URI: http://irep.iium.edu.my/id/eprint/20826

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