Immune-mediated oral mucosal pathology: a comprehensive review and update for clinicians. Part I

Al-Rashdan, Mohammad S and Arzmi, Mohd Hafiz and Ahmad Kamil, Wan N. and Al Kawas, Sausan and Leao, Jair C. (2023) Immune-mediated oral mucosal pathology: a comprehensive review and update for clinicians. Part I. Italian Journal of Dermatology and Venereology, 158 (5). pp. 408-418. ISSN 2784-8671 E-ISSN 2784-8450

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Abstract

the oral mucosa can be involved in a wide variety of mucocutaneous conditions that may present primarily in the mouth or affect other cu- taneous or mucosal sites. Many of these conditions are immune mediated and typically present as inflammatory mucosal pathology. Patients experiencing such conditions usually seek medical evaluation and treatment due to the associated pain and discomfort and occasionally taste disturbance or dysphagia and the overall deterioration in the oral health-related quality of life. these conditions share some common features and there could be some overlapping in their clinical presentation, which can lead to delays in diagnosis and proper management of patients. Clinicians dealing with such disorders, including dermatologists, need to be aware of the oral manifestations of mucocutaneous conditions, their clinical features, underlying mechanisms, diagnostic approaches, and treatment options, as well as the recent advances in the research on these conditions. this review provides a comprehensive, evidence-based reference for clinicians, with updated insights into a group of immune mediated conditions known to cause oral mucosal pathology. Part one will cover oral lichen planus, erythema multiforme and systemic lupus erythematosus, while part two will cover pemphigus vulgaris and mucous membrane pemphigoid, recurrent aphthous stomatitis, in addition to the less common disorders linear Iga disease, dermatitis herpetiformis and epidermolysis bullosa.

Item Type:	Article (Review)
Uncontrolled Keywords:	oral lichen planus; erythema multiforme; Systemic lupus erythematosus; Immune system diseases; mouth mucosa.
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Fundamental Dental and Medical Sciences
Depositing User:	AP Ts Dr Mohd Hafiz Arzmi
Date Deposited:	20 Nov 2023 11:04
Last Modified:	10 Mar 2024 14:04
URI:	http://irep.iium.edu.my/id/eprint/108245

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