Development and evaluation of a high-performance electrochemical potentiostat-based desktop application for rapid SARS-CoV-2 testing

Assaig, Faisal Ahmed and Gunawan, Teddy Surya and Nordin, Anis Nurashikin and Ab. Rahim, Rosminazuin and Mohd Zain, Zainiharyati and Mohd Zain, Rozainanee and Arifin, Fatchul (2023) Development and evaluation of a high-performance electrochemical potentiostat-based desktop application for rapid SARS-CoV-2 testing. Indonesian Journal of Electrical Engineering and Informatics (IJEEI), 11 (2). pp. 349-365. ISSN 2089-3272

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Abstract

The COVID-19 pandemic has necessitated the development of rapid and trustworthy diagnostic tools. Reverse transcription-polymerase chain reaction (RT-PCR) is the gold standard for detecting SARS-CoV-2 but has cost and time constraints. The sensitivity, specificity, and low cost of electrochemical biosensors make them an attractive alternative for virus detection. This study aims to develop and evaluate a high-performance desktop application for an electrochemical potentiostat-based SARS-CoV-2 test device, with a user-friendly interface that automatically interprets results, to expedite the testing process and improve accessibility, particularly in resource-limited settings. The application was built with the Electron framework and the HTML, CSS, and JavaScript programming languages. Our findings indicate that the developed electrochemical potentiostat-based desktop application demonstrates high accuracy compared to commercial software, achieving rapid detection within 30 seconds. The graphical user interface was found to be straightforward and user-friendly, requiring minimal training for efficient system operation. Our electrochemical potentiostat-based desktop application represents a valuable tool for rapid SARS-CoV-2 testing, particularly in settings with limited resources. This research contributes to developing rapid and reliable diagnostic tools for SARS-CoV-2 and potentially other pandemic-causing viruses, addressing the pressing need for improved public health surveillance and response strategies.

Item Type:	Article (Journal)
Uncontrolled Keywords:	SARS-CoV-2, Electrochemical potentiostat, Web technologies, Desktop application, Virus detection, Rapid testing, Cross-platform apps, User-friendly interface
Subjects:	T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK7800 Electronics. Computer engineering. Computer hardware. Photoelectronic devices > TK7885 Computer engineering
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Engineering Kulliyyah of Engineering > Department of Electrical and Computer Engineering
Depositing User:	Prof. Dr. Teddy Surya Gunawan
Date Deposited:	15 Nov 2023 09:39
Last Modified:	15 Nov 2023 10:14
URI:	http://irep.iium.edu.my/id/eprint/108083

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