Cytotoxic activity of Goniothalamus umbrosus on oral squamous cell carcinoma

Che Aziz, Nuraini and Mustafa Al-Ahmad, Basma Ezzat and Kashmola, Muhanad Ali Hamdon and Lestari, Widya (2023) Cytotoxic activity of Goniothalamus umbrosus on oral squamous cell carcinoma. In: International Conference on Natural Products (ICNP 2023), 11-13 Sept 2023, Kuala Lumpur, Malaysia. (Unpublished)

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Abstract

INTRODUCTION: The prevalence of oral cancer is increasing and has become a significant public health concern globally. This condition affects crucial functions such as eating, tasting, breathing, jaw movement, and speech, leading to serious health issues. In Malaysia, oral cancer is the nineteenth most frequently diagnosed cancer, with its occurrence varying depending on gender and ethnic group. G. umbrosus is consumed by Malaysian traditional folks for general well-being and to fight against tumour growth (Syahirah et al., 2016). To date, this plant has shown great anti-cancer potential against breast cancer cells, cervical cancer cells and leukemia cells (Toha et al., 2018; Sangrueng et al., 2015). RESEARCH GAP: However, to date, the cytotoxicity effect of this plant has never been tested on any oral squamous cell carcinoma cell lines. OBJECTIVE: This study aimed to evaluate the cytotoxic activity of G. umbrosus on oral squamous cell carcinoma cell line (SCC-15) and human gingival fibroblast cell line (HGF).

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	5816/106883
Uncontrolled Keywords:	Cytotoxic Activity, Goniothalamus umbrosus, Oral Squamous Cell Carcinoma
Subjects:	R Medicine > RK Dentistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Fundamental Dental and Medical Sciences
Depositing User:	Dr Basma Al-Ahmad
Date Deposited:	19 Sep 2023 17:07
Last Modified:	19 Sep 2023 17:07
URI:	http://irep.iium.edu.my/id/eprint/106883

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