3-Monochloropropane-1,2-diol (3-MCPD): a review on properties, occurrence, mechanism of formation, toxicity, analytical approach and mitigation strategy

Syed Putra, Sharifah Shahira and Basirun, Wan Jefrey and Elgharbawy, Amal A.M. and Hayyan, Maan and Al Abdulmonem, Waleed and Aljohani, Abdullah S. M. and Hayyan, Adeeb (2023) 3-Monochloropropane-1,2-diol (3-MCPD): a review on properties, occurrence, mechanism of formation, toxicity, analytical approach and mitigation strategy. Journal of Food Measurement and Characterization, 2023. pp. 1-13. ISSN 2193-4126 E-ISSN 2193-4134

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Abstract

3-Monochloropropane-1,2-diol (3-MCPD) is one of the most common food contaminants in processed oils which forms mostly during the deodorization step of edible oil refining process. It has been detected in many types of food products such as infant formula, margarine, bread and soy sauce, which could result in kidney and testicular damage. The presence of 3-MCPD contaminant have been occurring for more a decade, which warrants a maximum permissible amount of 2 µg/kg body weight in food products in national and international levels. The purpose of this review is to provide an overview in the past 12 years on its physicochemical properties, occurrence, potential precursors and formation mechanism of 3-MCPD in foodstuffs. The toxicity, its quantification methods and mitigation strategy are also reviewed with an emphasis on the applicability, efficiency and issues encountered during the analysis. This review provides an elucidation regarding 3-MCPDEs and their food safety implications.

Item Type:	Article (Journal)
Uncontrolled Keywords:	3-Monochloropropane-1,2-diol; Food products; Oil contaminant; Toxicity
Subjects:	Q Science > QD Chemistry T Technology > T Technology (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	International Institute for Halal Research and Training (INHART)
Depositing User:	Dr AMAL ELGHARBAWY
Date Deposited:	19 May 2023 08:36
Last Modified:	19 May 2023 08:36
URI:	http://irep.iium.edu.my/id/eprint/104642

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