Irfan, Nining Irfanita and Suwandi, Asrul and Mohd Zubir, Amir Zulhakim and Haris @ Harith, Muhammad Salahuddin and Jaswir, Irwandi and Lestari, Widya
(2022)
Gelatin-based hemostatic agents for medical and
dental application at a glance: a narrative literature
review.
The Saudi Dental Journal, 34 (8).
pp. 699-707.
E-ISSN 1013-9052
Abstract
Uncontrolled bleeding is linked to higher treatment costs, risk of post-surgical infection
and increased disease and death. Hemostatic agents are used to treat excessive bleeding. A good
hemostatic agent controls bleeding effectively, reduces the need for blood transfusion, removes
the need for systemic drugs to control bleeding, results in shorter surgery time, and reduces the cost
and length of hospital stay of the patient. Gelatin-based hemostatic agents have been widely used in
medical and dental procedures, owing to their biodegradability and biocompatibility, as well as
availability and low cost of raw materials. In this narrative literature review, we discuss the back-
ground and different types of gelatin-based hemostatic agents in medical and dental procedures, the
comparison of gelatin-based and non-gelatin-based hemostatic agents, and the usage and develop-
ment of enhanced or novel gelatin-based hemostatic agents. Gelatin-based hemostatic agents are
effective and important part of bleeding control, as evidenced by its wide application in medicine
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