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Optimization of process conditions for lactic acid recovery using organic base

Jamal, Parveen and Mel, Maizirwan and Abdul Karim, Mohamed Ismail and Syahida, N. (2008) Optimization of process conditions for lactic acid recovery using organic base. In: 4th Kuala Lumpur International Conference on Biomedical Engineering 2008. Springer-Verlag Berlin Heidelberg, pp. 875-878.

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Abstract

Lactic acid has a wide range of applications in food, pharmaceutical and cosmetics industries. The global market for lactic acid in foods is estimated at 275,000 tons with average annual growth of 10 per cent. The persistent demand of pure and naturally produced lactic acid in food and beverage applications attracted researcher’s interest towards process development for maximum recovery of lactic acid from fermentation broth. In this study, an organic base with appropriate diluent was used and optimization of process conditions was done by using central composite design from Statistica software to determine the optimum conditions for recovery of lactic acid. The effects of initial lactic acid concentration, pH, stirring rate, the amount of triisooctylamine in decanol, the ratio of organic phase volume to aqueous phase volume Vorg/Vaq, on the distribution coefficients of the lactic acid, KD,and the percentage extraction of lactic acid were investigated. The optimum process conditions showed maximum recovery of 94.47%, (w/w) and KD value was 17.12.

Item Type: Book Chapter
Uncontrolled Keywords: Lactic acid, distribution coefficient, optimization, organic base.
Subjects: T Technology > TP Chemical technology > TP248.13 Biotechnology
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Engineering > Department of Biotechnology Engineering
Depositing User: Prof.Dr. Parveen Jamal
Date Deposited: 17 Jan 2012 18:59
Last Modified: 28 Oct 2016 16:17
URI: http://irep.iium.edu.my/id/eprint/10036

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