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Development and evaluation of a cosmetic cream formulation containing annona muricata leaves extract

Omar, Nur Ain and Abd Razak, Fashli Syafiq and Tang, Cher Hing and Helaluddin, Abul Bashar Mohammed and Sarker, Md Zaidul Islam and Janakiraman, Ashok Kumar and Liew, Kai Bin (2021) Development and evaluation of a cosmetic cream formulation containing annona muricata leaves extract. Latin American Journal of Pharmacy, 40 (2). pp. 258-266. ISSN 0326-2383 E-ISSN 2362-3853

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Abstract

Cosmetics are being widely used globally for both woman and man. Annona muricata extract has strong anti-oxidant activity. Antioxidants can reduce the signs of aging and are known as antiaging and anti-wrinkles. The aim of the present study was to formulate and optimize a best formulation of the cosmetic cream containing Annona muricata leaves extract. The blank cream was prepared using various types of emulsifiers at various concentrations. The aqueous phase and oily phase were heated up separately by using water bath at 70 °C and mixed until homogenous. The blank cream was evaluated for their physical properties and stability. When methyl paraben was being substituted with benzyl alcohol, no bacterial growth was observed. The fulfillment of choosing the best formulation was based on the evaluations of microbial and physical stability. Cream 8 was the best formulation of the blank cream due to the fullfillment of the parameters of the evaluations. The formula of cream 8 was added with 2%, 5% and 10% of A. muricata leaves extract. The A. muricata cream was physically stable and showed anti-oxidant activity. The final product of A. muricata cosmetic cream can be a potential antioxidant cosmetic cream to be marketed in the future.

Item Type: Article (Journal)
Additional Information: 4478/93596
Uncontrolled Keywords: Annona muricata, anti-oxidant, cosmetic, cream, excipients, Glucamate Sse-20, Novemer EC-2-.
Subjects: Q Science > QD Chemistry
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica > RS192 Materia Medica-Pharmaceutical Technology
R Medicine > RS Pharmacy and materia medica > RS403 Materia Medica-Pharmaceutical Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User: Dr. A. B. M. Helal Uddin
Date Deposited: 09 Nov 2021 12:12
Last Modified: 09 Nov 2021 12:12
URI: http://irep.iium.edu.my/id/eprint/93596

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