Functionalized antimicrobial nanofibers: design criteria and recent advances

Hamdan, Nazirah and Yamin, Alisa and Wan Abdul Khodir, Wan Khartini and Abd Hamid, Shafida and Guarino, Vincenzo (2021) Functionalized antimicrobial nanofibers: design criteria and recent advances. Journal of Functional Biomaterials, 12 (4). p. 59. E-ISSN 2079-4983

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Abstract

The rise of antibiotic resistance has become a major threat to human health and it is spreading globally. It can cause common infectious diseases to be difficult to treat and leads to higher medical costs and increased mortality. Hence, multifunctional polymeric nanofibers with distinctive structures and unique physiochemical properties have emerged as a neo‐tool to target biofilm and overcome deadly bacterial infections. This review emphasizes electrospun nanofibers’ design criteria and properties that can be utilized to enhance their therapeutic activity for antimi‐ crobial therapy. Also, we present recent progress in designing the surface functionalization of an‐ timicrobial nanofibers with non‐antibiotic agents for effective antibacterial therapy. Lastly, we discuss the future trends and remaining challenges for polymeric nanofibers.

Item Type:	Article (Journal)
Uncontrolled Keywords:	nanofibers; electrospinning; surface functionalization; antimicrobial resistance; non‐antibiotic treatments
Subjects:	Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Department of Chemistry Kulliyyah of Science
Depositing User:	WAN KHARTINI WAN ABDUL KHODIR
Date Deposited:	01 Nov 2021 09:15
Last Modified:	25 Nov 2021 10:25
URI:	http://irep.iium.edu.my/id/eprint/93384

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