The effects of Tualang honey on sperm profile In mixed cholesterol diet administered rats

Hasan, Sakiinah and Abdul Rahim, Roslina and Alias, Mohd Afzal and Muhammad, Siti Aeshah @ Naznin and Abdullah, Nor Zamzila and Abdul Razak, Redzuan Nul Hakim (2021) The effects of Tualang honey on sperm profile In mixed cholesterol diet administered rats. In: YSN-ASM International Scientific Virtual Conference (ISVC) 2021, 29th March 2021 - 1st April 2021, Kuala Lumpur, Malaysia. (Unpublished)

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Abstract

Introduction: Hypercholesterolaemia is a recognised factor associated with male infertility. They have been shown to reduce the semen quality. The main recommendation for treatment is diet modifications. Tualang honey (TH) has proven to exert anti-inflammatory and anti-oxidative effects which may help to improve sperm parameters. Methods: Thirty male Sprague Dawley rats were divided into two groups, mixed cholesterol diet (12%CD;n=24) and standard diet (SD;n=6) and were fed for 16 weeks. Then, the rats in the 12%CD group were divided into four groups and continued with SD. Group A was untreated while group B, C and D were given TH at different doses (1.2, 2.4, and 3.0g/kg/day) for 4 weeks. Then, sperm profile analysis from the caudal epididymis was performed. Results: Group A showed significant decrease in sperm concentration, the percentage of total sperm motility, progressive motility, and viability compared to SD group (p<0.001). In contrast, all TH supplemented groups demonstrated significant improvement in the sperm parameters (p<0.001). The higher the dosage of TH given, the higher the improvements in sperm parameters (p<0.001). Conclusion: TH supplementation with diet modifications improved sperm profile parameters. From our findings, there is a need to further explore TH in improving male infertility associated with hypercholesterolaemia.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	5456/91474
Uncontrolled Keywords:	Mix cholesterol diet, Tualang honey, sperm profile
Subjects:	Q Science > QP Physiology R Medicine > R Medicine (General) R Medicine > RB Pathology R Medicine > RC Internal medicine > RC620 Specialties of Internal Medicine-Nutritional Diseases R Medicine > RC Internal medicine > RC627 Specialties of Internal Medicine-Metabolic Diseases R Medicine > RC Internal medicine > RC803 Specialties of Internal Medicine-Diseases of The Digestive System. Gastroenterology R Medicine > RM Therapeutics. Pharmacology R Medicine > RM Therapeutics. Pharmacology > RM147 Administration of Drugs and Other Therapeutic Agents R Medicine > RM Therapeutics. Pharmacology > RM214 Diet therapy. Diet and dietectics in disease R Medicine > RZ Other systems of medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Basic Medical Kulliyyah of Medicine > Department of Pathology & Lab Medicine Kulliyyah of Nursing Kulliyyah of Nursing > Department of Basic Medical Sciences for Nursing
Depositing User:	Dr ROSLINA ABDUL RAHIM
Date Deposited:	18 Aug 2021 11:49
Last Modified:	07 Apr 2022 09:52
URI:	http://irep.iium.edu.my/id/eprint/91474

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