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Type-2 diabetes mellitus individuals carry different periodontal bacteria

Ali, Tamanna and Rumnaz, Adity and Urmi, Umme Laila and Nahar, Shamsun and Rana, Masud and Sultana, Fahmida and Iqbal, Samiul and Muklesur Rahman, Mohammed and A Rahman, Nor Azlina and Islam, Salequl and Haque, Mainul (2021) Type-2 diabetes mellitus individuals carry different periodontal bacteria. Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 21 (e0107). pp. 1-10. ISSN 1519-0501 E-ISSN 1983-4632

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Abstract

Objective: To identify etiologic microbiota associated periodontal diseases among diabetes patients and the factors related to the most commonly identified bacteria species. Material and Methods: Periodontal plaque samples from 11 diabetic participants and 13 non-diabetic controls were collected to assess their aerobic and anaerobic bacterial growth. Different distinct colonies were identified by microscopic and 16srDNA sequencing. Pearson's chi-square tests were conducted to examine any association between categorical variables. Results: The diabetic subjects revealed a more intense plaque formation with a mean plaque index of 2.4 compared to 1.8 in non-diabetics. A total of 86 bacteria were isolated from 24 plaque samples, 44 were aerobic, and 42 were anaerobic. Only aerobic isolates, 22 from diabetic patients and 22 from non-diabetic patients, were evaluated in these analyses. Bacillus spp. (B. cereus mainly) and Klebsiella spp. (K. pneumoniae, K. aerogenes, K. oxytoca) were detected markedly higher in non-diabetic individuals than in diabetic subjects (p=0.026 and p=0.021, respectively). Some bacteria were only identified in the dental plaque of diabetic individuals, namely, Bacillus mojavensis, Enterobacter cloacae, Proteus mirabilis, Staphylococcus epidermidis, Staphylococcus hominis, Staphylococcus pasteuri, Streptococcus mutans, and Streptococcus pasteurianus. The presence of acid reflux and jaundice were significantly associated with the most common bacterial isolate, namely Bacillus spp., with the p-values of 0.007 and 0.001, respectively. Conclusion: Type-2 diabetes mellitus is associated with a higher amount of dental plaques. Periodontal plaque samples from diabetic and non-diabetic subjects possess differential microbial communities. Diabetic plaques contain more versatile microbes predominated by gram-positive streptococci and staphylococci.

Item Type: Article (Journal)
Uncontrolled Keywords: Oral Health; Periodontal Diseases; Periodontitis; Diabetes Mellitus, Type 2.
Subjects: Q Science > QR Microbiology
R Medicine > RK Dentistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Allied Health Sciences > Department of Physical Rehabilitation Sciences
Depositing User: Dr. Nor Azlina A. Rahman
Date Deposited: 07 May 2021 10:26
Last Modified: 07 May 2021 10:26
URI: http://irep.iium.edu.my/id/eprint/89742

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