Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?

Awaisu, Ahmed and Nik Mohamed, Mohamad Haniki and Noordin, NM and Abd. Aziz, Noorizan and Syed Sulaiman, Syed Azhar and Ahmad Mahayiddin, Aziah and Muttalif, Abdul Razak (2011) Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes? Value in Health, 14 (7). A283. ISSN 1524-4733 (O), 1098-3015 (P)

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Abstract

Objectives: The objective of this study was to document the impact of an integrated TB directly observed therapy short-course (DOTS) plus smoking cessation intervention (SCI) on HRQoL. Methods: This was a non-randomized controlled study (quasi experimental design) involving 120 TB patients who were current smokers at the time of TB diagnosis. Patients were assigned to either of two groups: conventional TB-DOTS plus smoking cessation intervention (SCIDOTS group) or conventional TB-DOTS only (DOTS group). The effects of the novel intervention on HRQoL were measured using EQ-5D questionnaire. Two-way repeated measure ANOVA was used to examine the effects. Results: When compared, participants who received the integrated intervention had a better HRQoL than those who received the conventional TB care. The SCIDOTS group had a significantly greater increase in EQ-5D utility score than the DOTS group during 6 months follow-up (mean± SD = 0.98 ± 0.08 vs. 0.91 ± 0.14, p = 0.006). Similarly, the mean scores for EQ-VAS showed a consistently similar trend as the EQ-5D indices, with the scores increasing over the course of TB treatment. Furthermore, for the EQ-VAS, there were significant main effects for group [F (1, 84) = 4.91, p = 0.029, η2 = 0.06], time [F (2, 168) = 139.50, p = <0.001, η2 = 0.62] and group x time interaction [F (2, 168) = 13.89, p = <0.001, η2 = 0.14]. Conclusions: This study provides evidence that an integrated TB-tobacco treatment strategy could potentially improve overall quality of life outcomes among TB patients who are smokers.

Item Type:	Article (Journal)
Additional Information:	5123/8836
Uncontrolled Keywords:	treatment comparisons, smoking cessation, EQ-5D, health related-quality of life
Subjects:	R Medicine > RA Public aspects of medicine R Medicine > RM Therapeutics. Pharmacology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmacy Practice
Depositing User:	Professor Dr. Mohamad Haniki Nik Mohamed
Date Deposited:	03 May 2013 09:35
Last Modified:	27 Jun 2013 11:47
URI:	http://irep.iium.edu.my/id/eprint/8836

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