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Risk of eczema, wheezing and respiratory tract infections in the first year of life: a systematic review of vitamin D concentrations during pregnancy and at birth

Mustapa Kamal Basha, Muzaitul Akmal and Abdul Majid, Hazreen and Nuguelis, Razali and Yahya, Abqariyah (2020) Risk of eczema, wheezing and respiratory tract infections in the first year of life: a systematic review of vitamin D concentrations during pregnancy and at birth. Plos One, 15 (6). pp. 1-18. ISSN 1932-6203

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Abstract

Background Allergic conditions and respiratory tract infections (RTIs) are common causes of morbidity and mortality in childhood. The relationship between Vitamin D status in pregnancy (mothers), early life (infants) and health outcomes such as allergies and RTIs in infancy is unclear. To date, studies have shown conflicting results. Objective This systematic review aims to gather and appraise existing evidence on the associations between serum Vitamin D concentrations during pregnancy and at birth and the development of eczema, wheezing, and RTIs in infants. Data sources PubMed, MEDLINE, ProQuest, Scopus, CINAHL, Cochrane Library and Academic Search Premier databases were searched systematically using specified search terms and keywords. Study selection Articles on the associations between serum Vitamin D concentrations during pregnancy and at birth and eczema, wheezing, and RTIs among infants (1-year-old and younger) published up to 31 March 2019 were identified, screened and retrieved. Results From the initial 2678 articles screened, ten met the inclusion criteria and were included in the final analysis. There were mixed and conflicting results with regards to the relationship between maternal and cord blood Vitamin D concentrations and the three health outcomes-eczema, wheezing and RTIs-in infants. Conclusion Current findings revealed no robust and consistent associations between Vitamin D status in early life and the risk of developing eczema, wheezing and RTIs in infants

Item Type: Article (Review)
Additional Information: 5497/87839
Uncontrolled Keywords: 25-Hydroxyvitamin D Levels; Allergic Disease; Asthma; Impact; Calcium; Food
Subjects: R Medicine > RG Gynecology and obstetrics > RG551 Pregnancy
R Medicine > RL Dermatology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Nursing > Department of Special Care Nursing
Depositing User: Dr. Muzaitul Akma Mustapa Kamal Basha
Date Deposited: 15 Jan 2021 14:53
Last Modified: 15 Jan 2021 14:53
URI: http://irep.iium.edu.my/id/eprint/87839

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