IIUM Repository

Mildly elevated alkaline phosphatase (ALP) - a liver tumour hint not to be missed

Mukhali, Hassan Basri and Shalihin, Mohd Shaiful Ehsan and Nik Anuar, Nik Mohd Nurhafizi and Mohd, Zailani and Aiman Anuar, Nabila (2021) Mildly elevated alkaline phosphatase (ALP) - a liver tumour hint not to be missed. Malaysian Journal of Medicine and Health Sciences, 17 (1). pp. 194-196. ISSN 1675-8544 E-ISSN 2636-9346

[img] PDF (SCOPUS) - Supplemental Material
Restricted to Registered users only

Download (337kB) | Request a copy
[img] PDF - Published Version
Restricted to Registered users only

Download (176kB) | Request a copy


Abstract Healthcare providers are responsible for performing medical check-ups, analyse and interpret patient's laboratory results. It is common for an initially asymptomatic patient to receive abnormal results including liver enzymes such as alkaline phosphatase (ALP). The concern in these patients is the cut-off value for mildly elevated levels that requires intervention. This paper reports a case of liver malignancy in a 32-year-old man who presented with a mild elevation of ALP level less than five times the upper limit of normal. The patient had no clinical symptoms. Early ultrasound liver assessment showed dilated common bile duct, which led to an urgent CT scan of the liver that revealed supportive features of fibrolamellar carcinoma. The patient was managed successfully with early partial hepatectomy that has saved him from morbidity and mortality of liver malignancy. Indeed, liver malignancy can be detected early in a health clinic from a further assessment of trivial elevation of ALP.

Item Type: Article (Case Report)
Additional Information: 6934/87701
Uncontrolled Keywords: Liver tumour, Alkaline Phosphatase, Hepatocellular Carcinoma
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC254 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RD Surgery
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011)
Depositing User: Dr Mohd Shaiful Ehsan Shalihin
Date Deposited: 11 Jan 2021 11:26
Last Modified: 11 Jun 2021 15:07
URI: http://irep.iium.edu.my/id/eprint/87701

Actions (login required)

View Item View Item


Downloads per month over past year