Ahmad Fuad, Fazia Adyani and Tanbin, Suriyea (2020) Interrogating novel compounds for improved anti-dengue therapies via inhibition of human hexokinase II (HKII). In: Nanotechnology Symposium 2020, 21st Feb. 2020, Kuala Lumpur, Malaysia. (Unpublished)
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Abstract
Dengue is one of the most fatal infectious diseases in the world, which is caused by dengue virus (DENV). Regrettably until now, specific treatment for the disease has not been established. It has been reported that a human glycolytic enzyme, the human hexokinase II (HKII) has a great impact in supporting viral replication in the host cell, thus the enzyme has been proposed as an anti-DENV drug target. The main aim of this research is to identify novel anti-DENV agents for the treatment of dengue disease through in silico screening and HKII enzymatic inhibition studies.
| Item Type: | Conference or Workshop Item (Poster) |
|---|---|
| Additional Information: | 7200/87224 |
| Uncontrolled Keywords: | Dengue virus, dengue therapies, human kexokinase II, anti-dangue |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry R Medicine > RM Therapeutics. Pharmacology |
| Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Engineering > Department of Biotechnology Engineering Kulliyyah of Engineering |
| Depositing User: | Dr Fazia Adyani Ahmad Fuad |
| Date Deposited: | 30 Dec 2020 09:59 |
| Last Modified: | 30 Dec 2020 09:59 |
| URI: | http://irep.iium.edu.my/id/eprint/87224 |
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