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Antimicrobial and antioxidant activities of a Malaysian medicinal plant Anisophyllea Disticha (Jack) Baill. and quantification of its phenolic constituents

Abdul Baria, Nurul Ashikin and Sahena, Ferdosh and Sarker, Md. Zaidul Islam (2020) Antimicrobial and antioxidant activities of a Malaysian medicinal plant Anisophyllea Disticha (Jack) Baill. and quantification of its phenolic constituents. Bangladesh Journal of Botany. ISSN 0253-5416 E-ISSN 2079-9926 (In Press)

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Abstract

The ethanolic extracts of different parts of Anisophyllea disticha were tested for antimicrobial capability using disc diffusion assay. The result revealed positive growth inhibitory activity, but was considered weak for all extracts against gram positive bacteria. Leaf extract displayed the highest zone of inhibition with values of 10.67 ± 0.58 and 8.67 ± 0.58 mm against Staphylococcus epidermidis and S. aureus, respectively. On the other hand, stem showed the highest amount of total phenolic content (TPC) (27.73 ± 4.10 mg GAE/g extract) and similar trend was also observed in antioxidant potential in terms of DPPH radical scavenging activity (66.20 ± 11.74%) and ferric reducing antioxidant power assay (FRAP) (203.63 ± 16.03 mg Fe(II)/g extract). High positive correlation was found between TPC and antioxidant activities, suggesting that phenolic compounds contribute to the antioxidant power of plant extracts. HPLC analysis identified and quantified gallic acid, p-coumaric, ferulic acid and quercetin in the extracts.

Item Type: Article (Journal)
Additional Information: 7165/86327
Uncontrolled Keywords: Anisophyllea Disticha (Jack) Baill.
Subjects: Q Science > Q Science (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science > Department of Plant Science
Kulliyyah of Pharmacy
Depositing User: Dr. Sahena Ferdosh
Date Deposited: 14 Dec 2020 09:13
Last Modified: 14 Dec 2020 09:13
URI: http://irep.iium.edu.my/id/eprint/86327

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