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Receptor-based combinatorial nanomedicines: a new hope for cancer management

Abul Barkat, Harshita and Abul Barkat, Md and Sachi Das, Sabya and Rizwanullah, Md. and Taleuzzaman, Mohamad and Ab. Hadi, Hazrina (2020) Receptor-based combinatorial nanomedicines: a new hope for cancer management. In: Handbook of Research on Advancements in Cancer Therapeutics. Advances in Medical Diagnosis, Treatment, and Care (AMDTC) Book Series . IGI Global, Hershey PA, USA, pp. 339-355. ISBN 2475-6628

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Nanotechnology-based drug-delivery systems, as an anticancer therapy tool, have shown significant potentials for the diagnosis and treatment of cancer. Recent studies have demonstrated that cancer therapy could be efficiently achieved by combinatorial therapies, approaches using multiple drug regimens for targeting cancers. However, their usages have been limited due to shorter half-lives of chemotherapeutic agents, insignificant targetability to tumor sites and suboptimal levels of co-administered conventional drug moieties. Thus, nanotechnology-based drug-delivery systems with effective targetability have played a crucial role to overcome the limitations and challenges associated with conventional therapies and also have provided greater therapeutic efficacy. Herein, the authors have focused on various drug-incorporated combinatorial nanocarrier systems, the significance of various receptors-associated strategies, and various targeted delivery approaches for chemotherapeutic agents.

Item Type: Book Chapter
Additional Information: 5589/85894
Uncontrolled Keywords: Receptor-based combinatorial nanomedicines,cancer management
Subjects: R Medicine > RS Pharmacy and materia medica > RS192 Materia Medica-Pharmaceutical Technology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Pharmacy Practice
Depositing User: Dr Hazrina Ab Hadi
Date Deposited: 11 Dec 2020 09:30
Last Modified: 20 Jan 2021 16:12
URI: http://irep.iium.edu.my/id/eprint/85894

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