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Microbial resistance movements: an overview of global public health threats posed by antimicrobial resistance, and how best to counter

Dhingra, Sameer and A Rahman, Nor Azlina and Pelle, Ed and Rahman, Motiur and Sartelli, Massimo and Hassali, Mohamed Azmi and Islam, Tariqul and Islam, Salequl and Haque, Mainul (2020) Microbial resistance movements: an overview of global public health threats posed by antimicrobial resistance, and how best to counter. Frontiers in Public Health, 8. pp. 1-22. E-ISSN 2296-2565

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Abstract

Antibiotics changed medical practice by significantly decreasing the morbidity and mortality associated with bacterial infection. However, infectious diseases remain the leading cause of death in the world. There is global concern about the rise in antimicrobial resistance (AMR), which affects both developed and developing countries. AMR is a public health challenge with extensive health, economic, and societal implications. This paper sets AMR in context, starting with the history of antibiotics, including the discovery of penicillin and the golden era of antibiotics, before exploring the problems and challenges we now face due to AMR. Among the factors discussed is the low level of development of new antimicrobials and the irrational prescribing of antibiotics in developed and developing countries. A fundamental problem is the knowledge, attitude, and practice (KAP) regarding antibiotics among medical practitioners, and we explore this aspect in some depth, including a discussion on the KAP among medical students. We conclude with suggestions on how to address this public health threat, including recommendations on training medical students about antibiotics, and strategies to overcome the problems of irrational antibiotic prescribing and AMR.

Item Type: Article (Journal)
Additional Information: 5509/84661
Uncontrolled Keywords: antibiotics, antimicrobial resistance, AMR, globe, public health, hazard
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RM Therapeutics. Pharmacology > RM300 Drugs and their action
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Allied Health Sciences
Kulliyyah of Allied Health Sciences > Department of Physical Rehabilitation Sciences
Depositing User: Dr. Nor Azlina A. Rahman
Date Deposited: 13 Nov 2020 15:04
Last Modified: 13 Nov 2020 15:04
URI: http://irep.iium.edu.my/id/eprint/84661

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