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Medicinal uses, phytochemistry, and pharmacological properties of Piper aduncum L.

Bakhtiar, M. Taher and Amri, Mohamad Shahreen and Darnis, Deny Susanti and Abdul Kudos, Muhammad Badri and Md Nor, Nur Fasya Ajda and Syukri, Yandi (2020) Medicinal uses, phytochemistry, and pharmacological properties of Piper aduncum L. Sains Malaysiana, 49 (8). pp. 1829-1851. ISSN 0126-6039

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Piper aduncum L., commonly known as ‘spiked pepper’, has various uses in traditional medicine that include treating wounds, skin boils, infections, and diarrhoea. Its properties as an anti-parasitic, antimicrobial, insecticidal, antitumor, and anticancer agent indicates that it could have further therapeutic potential in treating infections and cancers. The aim of this review was to provide a comprehensive summary of the traditional uses, phytochemistry and pharmacological properties of P. aduncum. Data were collected from electronic databases from 1978 to 2019. The plant is traditionally used for treating diarrhoea in Peru and for its wound-healing properties in Brazil and Papua New Guinea. Phenolics, monoterpenes, sesquiterpenes, and chromene have been found in the P. aduncum plant, and these bioactive compounds contribute to its anti-parasitic, antimicrobial, insecticidal, antitumor, and anticancer properties. Several pharmacological activities of P. aduncum have been reported, most notably in the treatment of infectious diseases and cancer. However, information regarding its safety and efficacy in humans is lacking. Further study is needed to examine the benefits of P. aduncum and its potential applications in a clinical setting.

Item Type: Article (Journal)
Additional Information: 5209/83158
Uncontrolled Keywords: Pharmacological properties; phytochemistry
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Kulliyyah of Science
Depositing User: Dr Muhammad Taher
Date Deposited: 24 Sep 2020 16:26
Last Modified: 24 Sep 2020 16:26
URI: http://irep.iium.edu.my/id/eprint/83158

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