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Association of disease knowledge and medication adherence among out-patients with Type 2 Diabetes Mellitus in Khobar, Saudi Arabia

AlShayban, Dhfer Mahdi and Naqvi, Atta Abbas and Alhumaid, Othman and AlQahtani, Ali Saad and Islam, Md. Ashraful and Ghori, Syed Azizullah and Haseeb, Abdul and Ali, Majid and Iqbal, Muhammad Shahid and Elrggal, Mahmoud E. and Ishaqui, Azfar Athar and Mahmoud, Mansour Adam and Khan, Irfanullah and Jamshed, Shazia Qasim (2020) Association of disease knowledge and medication adherence among out-patients with Type 2 Diabetes Mellitus in Khobar, Saudi Arabia. Frontiers in Pharmacology, 11. pp. 1-9. ISSN 1663-9812

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Objective: The study aimed to evaluate the association between disease knowledge and medication adherence in patients with type 2 diabetes mellitus. Methods: A cross-sectional study was conducted for three months, in patients with type 2 diabetes who visited three community pharmacies located in Khobar, Saudi Arabia. Patients’ disease knowledge and their adherence to medications were documented using Arabic versions of the Michigan Diabetes Knowledge Test and the General Medication Adherence Scale respectively. Data were analyzed through SPSS version 23. Chi-square test was used to report association of demographics with adherence. Spearman’s rank correlation was employed to report the relationship among HbA1c values, disease knowledge and adherence. Logistic regression model was utilized to report the determinants of medication adherence and their corresponding adjusted odds ratio. Study was approved by concerned ethical committee (IRB-UGS-2019-05-001). Results: A total of 318 patients consented to participate in the study. Mean HbA1c value was 8.1%. A third of patients (N = 105, 33%) had high adherence and half of patients (N = 162, 50.9%) had disease knowledge between 51% - 75%. A significantly weak-to-moderate and positive correlation (ρ = 0.221, p < 0.01) between medication adherence and disease knowledge was reported. Patients with >50% correct answers in the diabetes knowledge test questionnaire were more likely to be adherent to their medications (AOR 4.46, p < 0.01). Conclusion: Disease knowledge in most patients was average and half of patients had high-to-good adherence. Patients with better knowledge were 4 to 5 times more likely to have high adherence. This highlights the importance of patient education and awareness regarding medication adherence in managing diabetes. © Copyright © 2020 AlShayban, Naqvi, Alhumaid, AlQahtani, Islam, Ghori, Haseeb, Ali, Iqbal, Elrggal, Ishaqui, Mahmoud, Khan and Jamshed.

Item Type: Article (Journal)
Additional Information: 6803/82175
Uncontrolled Keywords: disease knowledge, medication adherence, patient compliance, concordance, diabetes mellitus out-patients, Saudi Arabia
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Pharmacy Practice
Depositing User: Dr Shazia Jamshed
Date Deposited: 14 Aug 2020 11:09
Last Modified: 14 Aug 2020 11:09
URI: http://irep.iium.edu.my/id/eprint/82175

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