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Phytochemical screening and antibacterial activity determination of peperomia pellucida extract

Ibrahim, Maizatul Akma and Mohamed Yahaya, Nor Ashikin (2020) Phytochemical screening and antibacterial activity determination of peperomia pellucida extract. Tropical Agrobiodiversity (TRAB), 1 (1). pp. 4-6. ISSN 2716-7046

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Antibiotics play a vital role in combating diseases caused by pathogenic bacteria. Consumption of antibiotics may emit certain undesirable side effects. Hence, there is an initiative to discover new novel natural products with therapeutic potential, which is safer and can combat various ailments. Peperomia pellucida, which belongs to Piperaceae family, is a herbal plant that can be found in many regions of tropical Asia. This study aimed to extract P. pellucida and screen its phytochemical compositions, and finally test its antibacterial activity on gram positive and gram-negative bacteria. Ethanolic extraction was conducted to obtain a crude extract of the leaf sample. Phytochemical test screenings were also carried out. Antibacterial assay by agar well diffusion was done for the antibacterial activity to determine the minimum inhibitory concentration (MIC). The results showed that the ethanolic leave extract of P. pellucida contains steroids and tannins. The extract exhibited the maximum inhibition zones of 15.67 ± 0.58 mm, 9.67 ± 1.58 mm and 10.67 ± 0.58 mm against E. coli, P. aeruginosa and S. aureus respectively. Based on the MIC test, the ethanolic leaf extracts have shown potential antibacterial activity.

Item Type: Article (other)
Additional Information: 7138/82106
Uncontrolled Keywords: Phytochemical, antibacterial, peperomia pellucida extract
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Q Science > QK Botany
Q Science > QR Microbiology
S Agriculture > S Agriculture (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science > Department of Plant Science
Depositing User: Dr Maizatul Ibrahim
Date Deposited: 11 Aug 2020 15:46
Last Modified: 11 Aug 2020 15:46
URI: http://irep.iium.edu.my/id/eprint/82106

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