Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women

Shafii, Noorazliyana and Omar, Julia and Kuttulebbai Naina Mohamed Salam, Sirajudeen and Yaacob, Najib Majdi and Abdullah, Mohamed Rusli (2020) Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women. International Medical Journal, 27 (2). pp. 148-150. ISSN 13412051

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Abstract

Abstract: Objective: C.striatus has been suggested to have antioxidant and anti-inflammatory properties for wound healing. This study was conducted to determine the level of Total Antioxidant Status (TAS) and the effectiveness of oral supplementation of C.striatus extract in post Lower Segment Caesarean Section (LSCS) patients during wound healing. Design: This was a randomized; double blinded, placebo-controlled study among post LSCS women conducted in Department of Obstetric and Gynaecology, Hospital Universiti Sains Malaysia from March 2010 to December 2012. Material and Methods: A total of 39 patients from C.striatus and 34 patients from placebo group were included in this study. After randomization, the treatment group consumed 500 mg of freeze dried C.striatus extract daily while the placebo group consumed 500 mg of placebo (maltodextrin) daily for 6 weeks. For each subject, venous bloods for TAS were taken postoperatively at day 1, day 3, week 2, week 4 and week 6. Repeated measure for analysis of variance (ANOVA) was used to determine the changes of TAS between and within both groups throughout the 6 weeks intervention. Results: The result suggested an increment of TAS level within C.striatus group from second week postoperative onwards which might involve in the enhancement of wound healing. Conclusion: The administration of C.striatus extract has beneficial effect during wound healing by enhancing the process in post-operative LSCS women.

Item Type:	Article (Journal)
Additional Information:	9547/81958
Uncontrolled Keywords:	channa striatus ; antioxidant ; wound healing ; caesarean ; women
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Basic Medical
Depositing User:	Prof.Dr. SIRAJUDEEN KUTTULEBBAI NAINAMOHAMED SALAM
Date Deposited:	05 Aug 2020 12:20
Last Modified:	11 Jan 2021 12:48
URI:	http://irep.iium.edu.my/id/eprint/81958

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