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Potential antibacterial effects of flaxseed and Nigella sativa extracts on 11 streptococcus pyogenes

Mustafa Al-Ahmad, Basma Ezzat and Mohamed Yusoff, Nurul Fatihah and Mustafa, Nazih Shaban and Subramaniam, Pram Kumar and Darnis, Deny Susanti and Mokhtar@Makhtar, Khairani Idah (2020) Potential antibacterial effects of flaxseed and Nigella sativa extracts on 11 streptococcus pyogenes. International Journal of Orofacial and Health Sciences, 1 (1). pp. 11-17. ISSN 2716-5434

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Abstract

Antibiotic resistance is a major global problem, associated with inadvertent drug usage. Herbal interventions are a therapeutic strategy that warrants greater research attention. Flaxseed and Nigella sativa are well recognized original super foods that have demonstrated potent anti-microbial and anti-biofilm activities. In the oral cavity, the bacterial population is a result of the dynamic relationship between pathogens and commensals Streptococcus pyogenes is an important global human Gram-positive pathogen that causes a wide variety of acute infections, it is highly virulent since it has the ability overcome the host defence system. This in vitro study aims to evaluate antimicrobial activity of flaxseed and Nigella sativa extract against S. pyogenes. Ethanolic extract of flaxseed and Nigella sativa extracts were prepared and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against S. pyogenes was estimated. The results of this study show that both extracts exhibited antibacterial activity against S. pyogenes. Present study demonstrated the bactericidal activity of both extracts which can be an adjunct to the future natural anti-bacterial therapy.

Item Type: Article (Journal)
Additional Information: 5816/81000
Uncontrolled Keywords: Antibacterial effect, flaxseed, Nigella sativa, Streptococcus pyogenes
Subjects: R Medicine > RK Dentistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Dentistry
Kulliyyah of Dentistry > Fundamental Dental and Medical Sciences
Kulliyyah of Dentistry > Paediatric Dentistry, Orthodontics & Dental Public Health
Kulliyyah of Science
Depositing User: Assoc Prof Khairani Idah Mokhtar
Date Deposited: 23 Jun 2020 17:15
Last Modified: 23 Jun 2020 17:16
URI: http://irep.iium.edu.my/id/eprint/81000

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