IIUM Repository

Intraocular pressure : the effect of short-term fasting and its association with fluid and fat status

Esa, Nur Raihan and Mohd Shukri, Nor Azwani and Ahmad, Norsham and Hilmi, Mohd Radzi and Md Mustafa, Md Muziman Syah and Ibrahim, Nura Syahiera and Che Arif, Fatin Amalina and Yusof @ Alias, Firdaus (2020) Intraocular pressure : the effect of short-term fasting and its association with fluid and fat status. Malaysian Journal of Medicine and Health Sciences, 16 (2). pp. 180-186. ISSN 1675-8544

PDF - Published Version
Download (349kB) | Preview
[img] PDF (SCOPUS)
Restricted to Repository staff only

Download (76kB) | Request a copy


Introduction: Short-term fasting may influence intraocular pressure (IOP) due to alteration of fluid (total body water; TBW, and water intake) and fat (total body fat; TBF). This study aimed: i) to compare IOP values within and between, fasting and non-fasting periods; and ii) to assess the association between IOP and, TBW and TBF. Methods: Thirty healthy participants aged 21.8±1.1 years were assessed on two different periods (fasting vs. non-fasting). During each period, the IOP, TBW and TBF values were assessed for four times (morning, afternoon, evening, late-evening). The IOP was measured using AccuPen® tonopen, while TBW and TBF were assessed by using a Tanita body composition analyser. Results: During fasting, the IOP value in the afternoon (14.53±2.33 mmHg) was significantly higher than in the evening (12.43±2.73 mmHg, p=0.009) and late-evening (12.60±2.44 mmHg, p=0.003). No significant difference in IOP was observed during non-fasting period. The mean of IOP in the evening was significantly lower during fasting compared to non-fasting (12.43±2.73 mmHg vs 13.75±2.53 mmHg, p=0.044). The IOP and TBW were negatively correlated (r=-0.268; p=0.011) during non-fasting and showed no association during fasting period. There was no significant correlation between IOP and TBF during both fasting and non-fasting periods. Conclusion: IOP reduction during short-term fasting, together with the no association with TBF and TBW suggested that IOP is an independent factor that reduces during fasting in healthy population.

Item Type: Article (Journal)
Additional Information: 4598/80483
Uncontrolled Keywords: Intraocular pressure, Fasting, Total body water, Total body fat, Total fat intake
Subjects: R Medicine > RE Ophthalmology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Allied Health Sciences
Kulliyyah of Allied Health Sciences > Department of Nutrition Sciences
Kulliyyah of Allied Health Sciences > Department of Optometry and Visual Science
Depositing User: Dr. Md Muziman Syah Md Mustafa
Date Deposited: 16 May 2020 14:37
Last Modified: 09 Aug 2023 14:20
URI: http://irep.iium.edu.my/id/eprint/80483

Actions (login required)

View Item View Item


Downloads per month over past year